Sildalis - What you need to know
Every medical condition has a wide range of drugs that can be used to treat it. They may differ in dosage, action mechanisms or side effects. There are also cases where a combination of more than one drug is essential in order to battle the disease or achieve a better result in general. One of the drugs that belong to this category is Sildalis, used to treat erectile dysfunction issues.
Sildalis is a combination of the two most popular chemical substances used to battle the condition, Sildenafil and Tadalafil, manufactured by the Indian company Dharam Distributors. It comes in pills containing 100 mg Sildenafil and 20 mg Tadalafil, summing up to a total of 120mg in a single dosage. Men that have used either one of the two in the past realize that this pill is very “strong”.
Both of the active ingredients are parts of the group that scientists have named “PDE5 inhibitors”. So their mechanism of action is similar. The goal is to prevent the action of the specific phosphodiesterase type 5 (PDE5) enzyme.
In order to achieve and maintain a normal erection, the male body produces nitric oxide and releases it in the corpus cavernosum, an area of the male genitals. This, in turn, “pairs” with guanylate cyclase to increase the concentration levels of cyclic guanosine monophosphate (cGMP). Men who suffer from erectile dysfunction have this chain of events interrupted because of the aforementioned enzyme. The PDE5 does not allow cGMP to increase thus making an erection impossible to happen. So, Sildenafil and Tadalafil are used to block the PDE5 and enable cGMP to increase its concentration level.
No matter what information the potential buyer gathers from various articles or other sources, it is strongly advised that the final consult and guidance before using Sildalis should come from a doctor.
There are a few groups of men who should not use erectile dysfunction drugs in general, including Sildalis. Some of these groups are the following:
- Men who have low blood pressure.
- Men who have an allergy or hypersensitivity to any of the drug’s ingredients.
- Men who suffer from chronic liver or kidney issues.
- Men who suffer from a chronic heart disease of any kind or have recently suffered a heart attack.
- Men who suffer from leukemia.
What most men may seriously be worried about are the side effects of such drugs. This is a common misconception since the occurrence of such events is rather rare. Still, knowing about them even though they may never appear is vital to the correct usage of the drug since it allows the user to be prepared to deal with them (side effects) without worrying or even feeling panic. Some of them are:
- Feeling of upset stomach.
- Sudden appearance of vision issues.
It is important to repeat that all of the above side effects are not the rule but the very rare exception. But even when they do appear, their duration is often limited since, most of the times, it is just a “natural” and expected reaction of the user’s body to the drug that entered the blood stream.
The recommended dosage of Sildalis is 1 tablet taken 1 hour up to 10 minutes prior to the sexual activity. However, as we have already mentioned, the chemical composition of the pill makes it very effective, thus the recommended quantity may be even less. It is a matter that is different from one man to another and should be clarified and set by the appropriate doctor.
Medicine offers us Sildalis, a combination of two separate drugs already available in the market in order to be able to treat even the most difficult cases of erectile dysfunction. The idea of combining existing drugs is not that original but succeeding in doing so is considered to be complicated since there is a wide range of factors that need to be taken into consideration. In our case, Dharam Distributors managed to overcome all obstacles and manufacture the pill. So now men who suffer from some erectile dysfunction issues have a really powerful remedy at their disposal.